Epidemiology Measures of Effect

Do you require help with your paper? Use our custom writing service to achieve better grades and meet your deadlines. Trust our team of writing experts with your work today, and enjoy peace of mind.


Order a Similar Paper Order a Different Paper

MEASURES OF EFFECT

Calculate and interpret measures of effect in different epidemiologic study designs.

A. A cohort study is conducted to assess the association between clinical characteristics and the risk of stroke. The study involves n=1250 participants who are free of stroke at the study start (baseline). The data in Table 4 below shows hypertensive status measured at baseline and incident stroke at five years.

Table 4. Hypertension status at baseline and stroke five years later

Stroke at 5 years

Hypertension at baseline

Yes (+)

No (-)

Yes (+)

18

234

No (-)

46

952

  1. Compute the prevalence of hypertension among study participants at baseline. Interpret.
  2. Compute the cumulative incidence of stroke in this study. Interpret.
  3. Compute the cumulative incidence of stroke in patients classified as hypertensive at baseline. Interpret.
  4. Compute the risk difference of stroke in patients with hypertension as compared to patients free of hypertension. Interpret.
  5. Compute the relative risk of stroke in patients with hypertension as compared to patients free of hypertension. Interpret.

B. A case control study is conducted to assess the relationship between heavy alcohol use during the first trimester of pregnancy and miscarriage. Fifty women who suffered miscarriage are enrolled along with 50 who delivered full-term. Each participant’s use of alcohol during pregnancy is ascertained. Heavy drinking is defined as four or more drinks on one occasion. The data are shown in Table 5.

Table 5. Alcohol use and outcome during pregnancy

Miscarriage

Heavy alcohol use

Yes (+)

No (-)

Yes (+)

14

4

No (-)

36

46

  1. Compute the odds of miscarriage in women with heavy alcohol use during pregnancy. Interpret.
  2. Compute the odds of miscarriage in women with no heavy alcohol use during pregnancy. Interpret.
  3. Compute the odds ratio of women with heavy alcohol use compared to women with no heavy alcohol use during pregnancy. Interpret.
Writerbay.net

Do you need help with this or a different assignment? We offer CONFIDENTIAL, ORIGINAL (Turnitin/LopesWrite/SafeAssign checks), and PRIVATE services using latest (within 5 years) peer-reviewed journal articles. Kindly click on ORDER NOW to receive an A++ paper from our masters- and PhD writers.

Get a 15% discount on your order using the following coupon code SAVE15


Order a Similar Paper Order a Different Paper